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RADIOTHERAPY IN GENERAL

Radiotherapy is a treatment modality used in the management of cancer. This modality uses high energy ionizing radiation to kill the cancer cells. The delivery of high doses of radiation to the tumour is intended to cure, control or reduce symptoms of the disease.

If you are afflicted with cancer, you would most probably be referred to a radiotherapy centre for treatment.

What Is Radiotherapy?

Radiotherapy (RT) is a treatment modality used in the management of cancer. This modality uses high energy ionizing radiation to kill the cancer cells. The delivery of high doses of radiation to the tumour is intended to cure, control or reduce symptoms of the disease. However, adjacent areas will also receive some of the radiation dose which can result in side-effects.

In cancer management, RT can be given alone or in combination with other modalities as follows:

  • Surgery
  • Chemotherapy
  • Hormone Therapy

 

How Is Radiotherapy Delivered?

Radiotherapy can be delivered by two methods:

  • Teletherapy (External Beam RT- EBRT)
  • Brachytherapy (Internal Beam RT- IBRT)

Teletherapy

In the delivery of this treatment method, radiation produced by machines called Linear Accelerators (or equipment that is similar), will be directed to the part of the body being treated.

Linear Accelerator (Teletherapy Machine) Patient undergoing Teletherapy

During treatment, the patient will lie on the treatment couch and several beams of radiation will be directed to the part of the body being treated from various angles as the Linear Accelerator is able to rotate around the patient.

Radiotherapy is given in a number of sessions in accordance to the doctor’s prescription and instructions. As an example, in the treatment for breast cancer, a radiation dose of 5000cGy is given in 25 fractions (times) within a period of five (5) weeks. Treatment prescription differs for various types of cancers and it also depends on the stage of the disease, patient’s physical condition and whether RT is combined with other modalities.

Patients can choose to travel from home or stay in the ward whilst undergoing EBRT.

Brachytherapy

Brachytherapy uses natural radioactive sources. Treatment is delivered by placing the sources, which produces radiation, within cavities, lumen, tissue or on the skin surface of the part of the body being treated.

High Dose Rate Brachytherapy Machine Patient undergoing brachytherapy

The radiation source is administered through a connecting tube which links the machine and special applicators placed within cavities, lumen and tissue. Special moulds are made from wax or other similar materials for the placement of applicators in the use of skin surface application.

Treatment is usually given in 2-4 sessions to achieve the required dose and is given once or twice a week. Brachytherapy is frequently used in the treatment of cervical, uterine and nasopharyngeal cancers and is used in combination with EBRT.

 

What Is The Objective Of Radiotherapy?

Whichever method is being used, either Teletherapy or Brachytherapy, radiotherapy is given to kill the cancer cells by destroying the DNA (deoxyribonucleic acid) to achieve the following treatment objectives:

  • Cure
  • Palliation (to control the disease and symptoms)

 

Side Effects Of Radiotherapy

Similar to other treatments, RT may also cause side effects to patients. This is because the normal cells within the area of treatment will also receive radiation. The side effects likely to develop will depend on the following factors:

  • Part of the body being treated.
  • Volume of tissue being treated.
  • Total dose given.
  • Combination of radiotherapy with other modalities such as chemotherapy.

Please refer to the side effects of RT.

 

The Radiotherapy Team

The radiotherapy team is multi-disciplinary, responsible for the management, treatment and care of the cancer patients.

  • Clinical Oncologist and Medical Officer

   – Responsible for the overall management, treatment and care of the cancer patients.

  • Physicist

  – Responsible  for quality assurance activities and radiation protection.

  – Development of treatment plans and dose calculations (Dosimetry).

  • Radiation Therapist (Therapy Radiographer)

  – Responsible for treatment planning (simulation) and treatment delivery for the patients.

  – Preparation of equipment and daily quality assurance of equipment.

  • Nurse

  – Responsible for the management and nursing care of patients in the clinic, wards and brachytherapy procedure room.

 

Radiotherapy Treatment Centres

The Ministry of Health provides radiotherapy services in the following centres:

 Institut Kanser Negara, Putrajaya

No 4, Jalan P7, Presint 7, 62250 Putrajaya

Tel. No.: 03-8892 5555

 

Jabatan Radioterapi dan Onkologi, Hospital Kuala Lumpur

Jalan Pahang, 50586 Kuala Lumpur

Tel. No.: 03-2615 5555

 

Pusat Rawatan Radioterapi dan Onkologi, Hospital Sultan Ismail

Jalan Persiaran  Mutiara Emas Utama, Taman Mount Austin, 81100 Johor Bharu, Johor

Tel. No.: 07-356 5000

 

Jabatan Radioterapi dan Onkologi, Hospital Umum Sarawak

Jalan Tun Ahmad Zaidi Adruce, 93586 Kuching, Sarawak

Tel. No.: 082-276 662

 

Jabatan Radioterapi dan Onkologi, Hospital Wanita dan Kanak-kanak, Likas

P.O. Box 187, 88996 Kota Kinabalu, Sabah

Tel. No.: 088-522 600

 

The Ministry of Education also provides radiotherapy services in the following centres:

  • Pusat Perubatan Universiti Malaya, Petaling Jaya, Selangor
  • Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur
  • Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan

There are several private radiotherapy centers available in the country. Please surf the website of the Malaysian Oncological Society (MOS) for further informations.

 

References

  1. Griffiths, S. & Short, C. (1994). Radiotherapy: Principles to Practice, Churchill Livingstone
  2. http://en.wikipedia.org/wiki/Ionizing_radiation
  3. http://www.mos

 

 

Last Reviewed : 23 March 2017
Translator : Rubiah binti Mohd Pakeh
Accreditor : Nafisah binti Hamid

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